This is a summary list of all resource providers at eagle-i Network Shared Resource Repository . The list includes links to more detailed information, which may also be found using the eagle-i search app.
ATCC is a private, nonprofit biological resource center (BRC) and research organization whose mission focuses on the acquisition, authentication, production, preservation, development and distribution of standard reference microorganisms, cell lines and other materials for research in the life sciences.
ATCC was established in 1925 when a committee of scientists recognized a need for a central collection of microorganisms that would serve scientists all over the world. The early years were spent at the McCormick Institute in Chicago until the organization moved to Georgetown University in Washington, DC in 1937. As research in the biosciences expanded, ATCC began to diversify its holdings, and as the collections grew ATCC occupied a series of sites, each providing more storage space. ATCC moved to its current state-of-the-art building in 1998.
Addgene is a non-profit organization dedicated to making it easier for scientists to share plasmids.
Addgene is reaching this goal by operating a plasmid repository for the research community. We are working with thousands of laboratories to assemble a high-quality library of published plasmids for use in research and discovery. By linking plasmids with articles, scientists can always find data related to the materials they request.
The main focus of the Becker lab has been on the mechanisms and consequences of post-ischemic myocardial inflammation.
We have found that the acute inflammation accompanying myocardial infarction begins shortly after reperfusion and enlarges the area of irreversible injury. Limiting inflammation by various means, such as with antibodies or drugs, can reduce infarct size and improve left ventricular function. Inflammation begins with conversion of endothelial cells in the ischemic myocardium to a pro-inflammatory phenotype, with increased expression of leukocyte adhesion proteins, such as intercellular adhesion molecule-1 (ICAM-1), and microvascular trapping of neutrophils with accumulation in the myocardium.
ICAM-1 gene upregulation in the post-ischemic myocardium is mediated by tumor necrosis factor alpha (TNFalpha) through the NFkB pathway, but also by activation (phosphorylation) of the transcription factor Stat3, bound to the transcriptional activator Sp1. Stat3 is phosphorylated in turn by interaction with Rac1, an essential subunit of the endothelial NADPH oxidase, through a novel multiprotein complex involving Stat3, Rac1, and protein kinase C (PKC).
Left ventricular hypertrophy (LVH) is one of the most potent risk factors for cardiovascular disease (CVD), including ischemic heart disease, chronic heart failure and CVD death. Common risk factors include hypertension and diabetes while a significant portion of the risk is also determined by genes. On a cellular level, studying cardiomyocytes (CMs) has yielded important insights into disease mechanism. There is now growing evidence suggesting that changes in the composition of the cardiac matrix particularly in diabetes contributes to the disease process in CMs. We propose to examine the role and impact of a 'diabetic' cardiac matrix, its interaction with cardiomyocytes and the role of genetic factors by using human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) as a `patient in a dish' model. Our proposal builds on extensive data which is available as part of the NHLBI HyperGen-LVH study. This includes GWAS and Whole Exome Sequence data. In addition, we have already developed hiPSC-CMs lines from 250 HyperGen participants. In Aim 1, we propose to culture hiPSC-CMs from these individuals on a matrix obtained from decellularized hearts of the db/db mouse to investigate cellular and molecular changes. In Aim 2 we perform expression analysis to determine global expression changes associated with the diabetic matrix followed by a pathway analysis to determine functional networks. Finally, in Aim 3, we perform eQTL analysis to determine single nucleotide polymorphisms (SNPs) associated with the response. Utilizing WES data, we will also perform a combined sequence and expression analysis to identify potential rare variants. Our proposal utilizes existing resources, including genetic and phenotypic data in addition to previously established hiPSC-CMs. Our experiments will provide novel insights into the molecular mechanisms underlying the cardiomyocyte-cardiac matrix interaction, its pathways and genetic factors modulating the response. A better understanding of the role of these interactions and networks can build the basis to develop novel treatment options as well as markers for the identification of individuals at increased risk. This becomes particularly important with an aging population and the increase in prevalence of diabetes.
CIRM hPSC Repository
The CIRM hPSC (human pluripotent stem cell) Repository, funded through a grant from the California Institute for Regenerative Medicine (CIRM), is a large publicly available human pluripotent stem cell bank with hundreds of different iPSC lines. The lines have been created for multiple diseases, representing diverse disease categories including autism spectrum disorders and other neurodevelopmental disabilities, blinding eye diseases, Alzheimer's disease, and liver, heart and lung diseases, as well as control samples. The iPSC lines are accompanied by detailed demographic and clinical data.
California's Stem Cell Agency was created in 2004 when 59% of California voters approved Proposition 71: the California Stem Cell Research and Cures Initiative. That initiative created the California Institute for Regenerative Medicine (CIRM) to fund stem cell research in the state. In addition to creating the agency, Prop 71 created a 29-member governing Board composed of researchers, business leaders and patient advocates.
CIRM held its first meeting in December, 2004 to begin hiring a president, finding a headquarters and establishing the three working groups to advise the board. The agency moved into headquarters in San Francisco in 2005 and issued the first round of funding in 2006.
In 2006, when CIRM first began funding awards, scientists knew very little about the best ways of working with stem cells or of converting them into mature cell types that would be useful as therapies. What’s more, funding restrictions from the federal governement and legal concerns prevented many scientists from dedicating their labs to regenerative medicine. As a result, few graduate and undergraduate students were learning how to work with the cells. This created a severe shortage in the future stem cell lab workforce.
The Center for Computational Biology (CCB) is focused on the development of computational biological atlases of different populations, subjects, modalities, and spatio-temporal scales.
The CCB develops novel mathematical, computational, and engineering approaches to map biological form and function in health and disease. CCB computational tools integrate neuroimaging, genetic, clinical, and other relevant data to enable the detailed exploration of distinct spatial and temporal biological characteristics. Generalizable mathematical approaches are developed and deployed using Grid computing to create practical biological atlases that describe spatiotemporal change in biological systems. The efforts of CCB make possible discovery-oriented science and the accumulation of new biological knowledge.
The mission of the Center for Multiscale Analysis of Genomic and Cellular Networks (MAGNet) is to develop novel structural biology and systems biology methods and tools for the dissection of molecular interactions in the cell and for the interaction-based elucidation of cellular phenotypes. These tools are made freely available to the the members of the research community. They are also validated in the context of the Center's own research program through collaborative projects with experimental biologists.
We are a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education.
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.
We are interdisciplinary researchers with diverse backgrounds based in the Department of Computer Science at the University of Victoria. Our offices are located in the Engineering/Computer Science building.
Our research interests include:
- cognitive support and technology diffusion
- human computer interaction
- human and social implications of technology use
- interface design
- knowledge engineering
- software engineering
- technology and pedagogy
Our primary objective is to develop tools that support people in performing complex cognitive tasks. Our projects benefit from the collaborative approach taken within our group and with other researchers. As a group, we operate by thinking creatively, exploiting our synergies, and applying innovative research techniques.
Coriell Institute for Medical Research, founded in 1953 and based in Camden, New Jersey, is an independent non-profit research center dedicated to the study of the human genome. Expert staff and pioneering programs in the fields of personalized medicine, cell biology, cytogenetics, genotyping, and biobanking drive our mission.
About Cowan Lab's Next Gen Cell Lines
This collection, from Dr. Chad Cowan (Harvard Stem Cell Institute), was generated to confirm identified variants through differentiation of induced pluripotent stem cells to study cellular pathophysiology.
The Framingham Heart Study has provided knowledge about the epidemiology of hypertensive or arteriosclerotic cardiovascular disease. These cell lines may be useful in studying cardiovascular disease.
Peripheral blood mononuclear cells from 34 Framingham Heart Study (FHS) Offspring, Exam 9 or Omni I, Exam 4 Cohort participants were reprogrammed into iPSC lines. Upon initial deposit of this collection, 17 participants were homozygous for the major haplotype at the 1p13 locus and 17 participants were homozygous for the minor haplotype at the 1p13 locus. Two clones from each donor were further expanded resulting in a total of 68 iPSC lines. The focus of deriving these cell lines was to differentiate iPSC lines into hepatocytes and adipocytes to investigate the effect of the 1p13 rs12740374 variant on cardiometabolic disease phenotypes via transcriptomics and metabolomics signatures. The age of donors ranges from 51-90 years. To protect donor identity, an age range rather than exact age is provided.
Please see Table S1 from the publication describing this collection of cell lines for additional information on these cell lines including:
• 1p13 Genotype
• Average Adipocyte Differentiation Efficiency
• Average Hepatocyte-like Cells (HLC) Differentiation Efficiency
Application to and approval by the Framingham Heart Study is necessary to receive these cell lines. You can being your research application here.
About the Next Generation Genetic Association Studies (Next Gen) Program
These cell lines were created as Next Generation Genetic Association Studies (Next Gen) Program, which was a five-year, $80 million program to investigate functional genetic variation in humans by assessing cellular profiles that are surrogates for disease phenotypes. To achieve this, researchers from multiple institutions across the U.S. were awarded grants to derive iPS cell lines from more than 1,500 individuals representing various conditions as well as healthy controls for use in functional genomic (‘disease in a dish’) research. This extensive panel includes a diverse set of age, gender and ethnic backgrounds, and therefore will be an invaluable tool for evaluations across demographics. Further enhancing the utility of these cell lines are data sets such as phenotyping, GWAS, genome sequencing, gene expression and -omics analyses (e.g., lipidomic, proteomic, methylomic) that will be made available with the cell lines.
The Developmental Studies Hybridoma Bank:
* was created by NIH as a national resource,
* sells at cost (e.g. 1 ml of supernatant costs $32.00, not $200.00 or more),
* is growing at 10% to 20% per year,
* has been given the distribution rights for monoclonals being generated by an NCI initiative in diagnostics, and
* has begun a second bank for microbes (DSHB-Microbe).
The research ambitions of our diverse faculty, staff and students are motivated by 21st century challenges. Drexel takes pride in supporting multidisciplinary research initiatives that change over time, and that bring together faculty with the breadth of expertise necessary to tackle complex and challenging issues.
The Duke Center for Human Genetics is an international leader in the study of inherited disorders. Our faculty and staff investigate genetic and environmental influences on human disease in a uniquely integrated research setting. Understanding the causes of human illness allows scientists and physicians to develop better treatments. Genetic research may uncover ways to slow the progression of a disease or prevent symptoms from ever appearing. Therefore, our long-term goal is the incorporation of genetic research findings into the diagnosis, treatment, and prevention of disease.
The Duke Translational Medicine Institute (DTMI) is Duke’s academic home for the clinical and translational research community. It is an integrated support structure that provides resources and training and facilitates collaborative research in clinical and translational research.
Our mission is to improve individual and population health by catalyzing translation across the continuum of scientific discovery, clinical research, care delivery, and global health. We facilitate team science by joining multidisciplinary investigators and industrial-model project management, while providing investigators easy access to emerging technologies and methodologies.
Home of the Blue Devils, Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world.
Located in the Leichtag Biomedical Research Building on UCSD’s main campus, the Frazer Laboratory’s research focuses on the genetics and functional genomics of cardiovascular diseases and cancer. Our research mission is to identify common and rare genetic variants that are associated with human disease in order to functionally assess their role in disease pathogenesis, progression, and prognosis. With our discoveries we hope to accelerate the translation of genomic research into clinical therapies and applications.
Freie Universität Berlin is a leading research institution. It is one of the German universities successful in all three funding lines in the federal and state Excellence Initiative, thereby receiving additional funding for its institutional future development strategy.
Freie Universität can thus take its place as an international network university in the global competition among universities. Development and assessment of research projects takes place within various focus areas, research networks, and platforms for interdisciplinary collaborative research.
In 1982, The Johns Hopkins Sibling and Family Heart Study was created to study patterns of coronary heart disease in high risk families. In 2015, the GeneSTAR Center extends its research to better understanding risk factors, genomics, biological models, and cellular science to better understand the causes of heart disease and stroke.
The primary goals in the Goldstein lab are to unravel how molecular motors interact with, and control the behavior of, axonal vesicles, and to relate this understanding to the molecular basis of neuronal defects in Alzheimer's Disease (AD) and Niemann Pick type C disease.
HHMI is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems. Headquartered in Chevy Chase, MD, HHMI employs more than 3,000 individuals across the United States. In fiscal year 2012, HHMI invested $695 million in U.S. research and provided $78 million in grants and other support for science education.
The Icahn School of Medicine at Mount Sinai is an international leader in medical and scientific training, biomedical research, and patient care. It is the medical school for the Mount Sinai Health System, which includes seven hospital campuses, and has more than 5,000 faculty and nearly 2,000 students, residents and fellows. Our unwavering pursuit of intellectual exchange, breakthrough research, and multidisciplinary teamwork propels us ever forward in biomedical discoveries and advances. We pursue ideas that often challenge conventional wisdom to revolutionize the practice of medicine and produce dramatically better outcomes for patients. We make big, bold bets by investing in radical free thinkers and technology at the cutting edge.
The hESC core facility has been established to facilitate the transfer of this technology to the Mount Sinai community and other NY state affiliated institutions.
Consistently rated amongst the world's best universities, Imperial College London is a science-based institution with a reputation for excellence in teaching and research.
Indiana University is a major multi-campus public research institution, grounded in the liberal arts and sciences, and a world leader in professional, medical, and technological education. Indiana University’s mission is to provide broad access to undergraduate, graduate, and continuing education for students throughout Indiana, the United States, and the world, as well as outstanding academic and cultural programs and student services. Indiana University seeks to create dynamic partnerships with the state and local communities in economic, social, and cultural development and to offer leadership in creative solutions for 21st century problems. Indiana University strives to achieve full diversity, and to maintain friendly, collegial, and humane environments, with a strong commitment to academic freedom.
Keele University places high value on research excellence and supports internationally competitive expertise throughout the Natural Sciences, Health, Humanities and Social Sciences. We are proud of our achievements in high quality, multidisciplinary research.
We have a unique commitment to research and enterprise. Our ethos is to make a global difference with research knowledge that has beneficial outcomes to solve problems – whether in combating malaria, research on ageing society or discovering new planets.
Reagents for the Greater Good
Our mission is to grow and foster a global community of scientists advancing life science research by facilitating access to bioresearch materials directly from the scientific community.
We are committed to reinvesting back into research by returning a portion of the sale to the scientists and their institutions that contribute Reagents for the Greater Good. We encourage the community to further scientific progress by providing or procuring novel bioresearch materials, which allows scientists to accelerate their own research and enable other researchers to access materials they need. Since any Procurer can also be a Provider, the entire interconnected community benefits the Greater Good of Science.
How it Works
These rare and often one-of-a-kind research materials are not developed or manufactured by Kerafast, but produced by principal investigators in the course of their work. These materials may be in limited supply, but may be just what your experiments require, and we expedite their delivery through a rapid online material transfer ‘click license’ agreement for research use.
Kinkaid's mission is to promote educational excellence, personal responsibility, and balanced growth, and thereby to help its students to discover and develop their talents and to fulfill their best potentials.
The Laboratory for Informatics Development (LID) supports the clinical research community through a number of biomedical informatics programs and initiatives.
LeTourneau University is an interdenominational Christ-centered university offering more than 80 programs that prepare students for success in areas including the arts and sciences, aviation, business, education and engineering. Graduate degree offerings include business, education, engineering and psychology.
The Lerner Research Institute is home to all laboratory-based, translational and clinical research at Cleveland Clinic. Our mission is to understand the underlying causes of human diseases and to develop new treatments and cures.
Through its biomedical informatics research, the Lister Hill National Center for Biomedical Communications (LHNCBC) develops advanced health information resources and software tools that are widely used in biomedical research and by health IT professionals, health care providers, and consumers. Established by a joint resolution of the United States Congress in 1968, LHNCBC is an intramural research and development division of the US National Library of Medicine (NLM). Seeking to improve access to high quality biomedical information for individuals around the world, the LHNCBC conducts and supports research and development in the dissemination of high quality imagery, medical language processing, high-speed access to biomedical information, intelligent database systems development, multimedia visualization, knowledge management, data mining, and machine-assisted indexing.
The Mouse Metabolic and Phenotyping Core is a comprehensive fee-for-service rodent phenotyping core that contains a multitude of testing capabilities for the assessment of rodent models from embryo to adult. Access to the MMPC is open to all Baylor and non-affiliated Baylor investigators. We provide investigators with a wide variety of state of the art equipment and techniques with the goal to standardize key methodologies, and to expedite comprehensive research analyses on diseases related to cancer, cardiovascular dysfunction, metabolic disorders, mouse models of human disease and drug studies. The MMPC supports the application of advanced analysis of metabolic pathways and related physiological and biochemical parameters in mice and rats, as well as in isolated / cultured cells in vitro. Assays offered include hyperinsulinemic-euglycemic clamp in conscious mice, oxygen consumption rate and extra cellular acidification rate measurements from cells in culture plates, DEXA and Echo MRI, CLAMS, heat and real time body temperature monitoring, home cage activity monitoring, MRI, CT, ultrasound, Xray, bioluminescence imaging, indirect calorimetry, telemetry, and non-invasive blood pressure measurements.
The Human Genetic Cell Repository, sponsored by the National Institute of General Medical Sciences, provides scientists around the world with resources for cell and genetic research. The samples include highly characterized cell lines and high quality DNA. Repository samples represent a variety of disease states, chromosomal abnormalities, apparently healthy individuals and many distinct human populations.
NINDS fibroblast and iPSC cell lines previously available from the NINDS Repository at Coriell can now be ordered through the NINDS Human Cell and Data Repository (NHCDR) at Rutgers.
Cell line requests that were received prior to the transition will be fulfilled by the NHCDR beginning the week of April 25th, 2016.
If cell lines were previously received from Coriell and the recipient is now requesting permission to distribute these lines to a third party, please forward these requests to NINDS@dls.rutgers.edu.
For specific details about existing requests please contact Dr. Michael Sheldon firstname.lastname@example.org.
"The NINDS Repository offers human induced pluripotent stem cell (iPSC) lines to further research on neurological disorders. The iPSC lines were derived from fibroblasts using a variety of reprogramming methods and submitted to the NINDS Repository. Each iPSC line is accompanied by a Certificate of Analysis prepared by the Coriell SCB."
The National Alliance for Medical Image Computing (NA-MIC) is a multi-institutional, interdisciplinary team of computer scientists, software engineers, and medical investigators who develop computational tools for the analysis and visualization of medical image data. The purpose of the Center is to provide the infrastructure and environment for the development of computational algorithms and open-source technologies, and then oversee the training and dissemination of these tools to the medical research community.
The goal of the National Center for Biomedical Ontology is to support biomedical researchers in their knowledge-intensive work, by providing online tools and a Web portal enabling them to access, review, and integrate disparate ontological resources in all aspects of biomedical investigation and clinical practice. A major focus of our work involves the use of biomedical ontologies to aid in the management and analysis of data derived from complex experiments.
Funded by the National Institutes of Health Blueprint for Neuroscience Research in 2006, the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) facilitates finding and comparing neuroimaging resources for functional and structural neuroimaging analyses—including popular tools as well as those that once might have been hidden in another researcher's laboratory or some obscure corner of cyberspace. NITRC collects and points to standardized information about tools, making the task of finding and comparing them easier than before. Awarded 'Best Overall' for Excellence.Gov 2009, this site can help you find the right functional or structural neuroimaging tool or resource and help you decide whether it can help in your research.
The New York Stem Cell Foundation (NYSCF) is a non-profit organization whose mission is to accelerate cures for the major diseases of our time through stem cell research.
To participate in a study please contact:
Human Subjects Research Office
The Quertermous laboratory is interested in the molecular mechanisms that mediate vascular disease pathophysiology and the risk for these diseases. The approach is primarily genetic, using human cohorts and large scale genome wide studies to identify genes that associate with disease and risk, and molecular genetic studies to define the mechanisms of these associations. At the human level, we collaborate with a number of centers around the world through the CARDIoGRAM+C4D consortium to further identify coronary heart disease loci, and our group serves as the the organizing center searching for loci that associate with gold standard measures of insulin sensitivity, the GENESIS study. For loci identified through these studies, we work to identify mechanisms by which causal variation is responsible for altered gene structure or function, and employ cellular and genetic mouse models to identify how encoded factors participate in the disease process. One novel approach to understanding the link between genes and human disease is employing induced pluripotent stem cells to create disease relevant cell types in vitro that can be studied in relationship to the subjects' phenotype and genetic architecture.
Our research program seeks to identify the cellular and molecular programs regulating vascular and lung development. We then determine how these programs are perturbed by genetic abnormalities or injurious processes associated with disease. Our studies use high throughput genomic and microfluidic technologies, a variety of cell biology platforms including confocal and videomicroscopy, genetically modified mouse models of human disease, human tissue samples and induced pluripotent stem cells to answer these questions. Our major disease focus is pulmonary arterial hypertension (PAH), a condition that can be a fatal complication in children with heart defects, but also arises as a condition of unknown etiology primarily in young women. The pathological changes in the lung blood vessels that cause right-sided heart failure include loss of the distal microcirculation and obliterative proliferative changes occluding the lumen of larger arteries. Our goal is to learn how we can activate lung vascular developmental programs to regenerate lost microvessels and to reverse the obliterative changes. Over the past decade our research has led to four novel compounds in clinical trial or being positioned for clinical trial.
The Rader laboratory is focused on two major themes: 1) novel pathways regulating lipid and lipoprotein metabolism and atherosclerosis inspired by unbiased studies of human genetics; 2) factors regulating the structure and function of high density lipoproteins and the process of reverse cholesterol transport and their relationship to atherosclerosis. A variety of basic cell and molecular laboratory techniques, mouse models, and translational research approaches are used in addressing these questions.
As the world’s largest university-based biorepository, RUCDR has been perfecting the science of biobanking, bioprocessing and analytics since 1999. By utilizing a technologically advanced infrastructure and the highest quality biomaterials, RUCDR scientists work to convert precious biosamples into renewable resources thereby extending research capabilities. RUCDR understands that research goals and objectives vary from project to project so we give each client individual and customized attention to ensure “best fit” service. Contact us to learn what we can do for you.
The Scripps Research Institute (TSRI) — one of the world's largest, private, non-profit research organizations — stands at the forefront of basic biomedical science, a vital segment of medical research that seeks to comprehend the most fundamental processes of life.
The Scripps Translational Science Institute (STSI) aims to replace the status-quo of one-size-fits-all-medicine with individualized health care that is based on the known genetic factors influencing health and disease and that takes advantage of advances in digital technology for real-time health monitoring.
Under the leadership of Eric J. Topol, M.D., one of the world’s premier cardiologists and physician/scientists, STSI has created major programs in both research and education-training that bridge science with medicine, and academia with industry.
These programs accelerate integration and innovation by emphasizing the three dimensions of translation:
• Traditional bench to bedside,
• Bedside to bench and back to bedside, and
• Bedside to the community and the practice of medicine.
The mission of Seoul National University in the twenty-first century is to create a vibrant intellectual community where students and scholars join together in building the future. As Korea's leading research university, Seoul National University is committed to diversifying its student body and faculty, fostering global exchange, and promoting path-breaking research in all fields of knowledge.
Simbios is the NIH Center for physics-based Simulation of Biological Structures. Simbios provides infrastructure, software, and training to help biomedical researchers understand biological form and function as they create novel drugs, synthetic tissues, medical devices, and surgical interventions.
Stanford University is one of the world's leading research universities. Stanford is known for its entrepreneurial character, drawn from the legacy of its founders, Jane and Leland Stanford, and its relationship to Silicon Valley. Research and teaching stresses interdisciplinary approaches to problem solving. Areas of excellence range from the humanities to social sciences to engineering and the sciences. Stanford is located in California's Bay Area, one of the most intellectually dynamic and culturally diverse areas of the nation.
The ability to genotype millions of polymorphisms in thousands of individuals and to sequence entire genomes affords the opportunity to understand how human diversity is associated with many diseases and longevity. It is also possible to direct the differentiation of patient-specific induced pluripotent stem cells, or iPSCs to erythroid progenitors that mature to produce hemoglobin. Both genomics and new iPSC technology can be used to study the molecular basis of phenotypic heterogeneity. This knowledge will then allow the development of predictive networks and genetic risk scores that can be used prognostically and point to functional studies of interesting variants and novel pathways that might can lead to new treatment options. We are taking this approach to the study of hemoglobin disorders focusing on sickle cell disease.
This is a temporary test organization for testing the google analytics work. SKC 10/11/16
My research is on indvidualized medicine, using the genome and digital technologies to understand each person at the biologic, physiologic granular level to determine appropriate therapies and prevention. An example is the use of pharmacogenomics and our research on clopidogrel (Plavix). By determining the reasons for why such a large proportion of people do not respond to this medication, we can use alternative treatment strategies to prevent blood clots.
The UC Davis/NIH NeuroMab Facility is an NIH-funded non-profit resource whose mission is to generate, validate and distribute high-quality mouse monoclonal antibodies that are optimized for research use in mammalian brain (NeuroMabs).
"This lab at UCLA does research into the relationship between brain structure and function using image data."
Moving from UCLA to USC.
The University of California was chartered in 1868 and its flagship campus — envisioned as a "City of Learning" — was established at Berkeley, on San Francisco Bay. Today the world's premier public university and a wellspring of innovation, UC Berkeley occupies a 1,232 acre campus with a sylvan 178-acre central core. From this home its academic community makes key contributions to the economic and social well-being of the Bay Area, California, and the nation.
UC San Diego is dedicated to the advancement of knowledge through excellence in education and research at the undergraduate, graduate, professional school and postdoctoral levels. The campus is committed to community engagement, public service and industry partnerships in order to advance the health and well-being of our region, state, nation and the world. Our academic community of world-renowned faculty, bright students and dedicated staff is characterized by a culture of interdisciplinary collaboration and innovation which spans the globe.
UCSF's innovative, collaborative approaches for patient care, research and education span disciplines across the life sciences and make it a world leader in scientific discovery and its translation into improved health.
The University of California, Santa Barbara is a leading research institution that also provides a comprehensive liberal arts learning experience. Because teaching and research go hand in hand at UC Santa Barbara, our students are full participants in an educational journey of discovery that stimulates independent thought, critical reasoning, and creativity. Our academic community of faculty, students, and staff is characterized by a culture of interdisciplinary collaboration that is responsive to the needs of our multicultural and global society. Our commitment to public service is manifested through the creation and distribution of knowledge that advances the well-being of our state, nation, and world. All of this takes place within a living and learning environment like no other, as we draw inspiration, opportunity, and advantage from the beauty and resources of UC Santa Barbara's extraordinary location at the edge of the Pacific Ocean.
The UConn Health Center is a vibrant, integrated academic medical center that is entering an era of unprecedented growth in all three areas of its mission: academics, research, and clinical care.
The University of Delaware exists to cultivate learning, develop knowledge and foster the free exchange of ideas. State-assisted yet privately governed, the University has a strong tradition of distinguished scholarship, research, teaching and service that is grounded in a commitment to increasing and disseminating scientific, humanistic and social knowledge for the benefit of the larger society.
The University of Iowa is a major national research university located on a 1,900-acre campus in Iowa City in southeast Iowa, on the Iowa River near the intersection of U.S. Interstate Highways 80 and 380. Iowa is composed of 11 colleges, the largest of which is the College of Liberal Arts and Sciences, enrolling most of Iowa's undergraduates. The Henry B. Tippie College of Business, the Roy J. and Lucille A. Carver College of Medicine, and the Colleges of Education, Engineering, Law, Nursing, Pharmacy, enroll undergraduates, and with the Colleges of Dentistry and Public Health provide graduate education in conjunction with the Graduate College.
The University of Notre Dame provides a distinctive voice in higher education that is at once rigorously intellectual, unapologetically moral in orientation, and firmly embracing of a service ethos.
The University of Queensland (UQ) is in the top 100 universities worldwide, measured through a number of major independent university rankings: the Academic Ranking of World Universities, Times Higher Education World University Rankings, QS World University Rankings and, Performance Ranking of Scientific Papers for World Universities. UQ is also the largest university in Queensland.
One of the nation's top academic medical centers, the University of Rochester Medical Center forms the centerpiece of the University's health research, teaching, patient care, and community outreach missions. With more than $145 million in federal research funding, UR School of Medicine research funding ranks in the top one-quarter of U.S. medical centers, while the School of Nursing ranks 12th highest in funding.
Research is a major component in the life of the U, benefiting students as well as the region. The University of Utah is ranked 47th in the U.S. (of 108 research universities) and 82nd in the world (of over 500 research universities) in the 2012 Academic Ranking of World Universities.
Founded in 1861 by a private gift of 10 acres in what is now the heart of downtown Seattle, the UW is one of the oldest public universities on the West Coast.
We’re deeply committed to upholding the responsibility that comes with that legacy. And being public has always meant being accessible.
UW–Madison ranks as one of the most prolific research universities in the world. Driven by a desire to both explore new worlds and to apply new ideas to real-world problems, research at UW–Madison isn't conducted only by faculty, staff and graduate students. Undergraduate research opportunities also are fostered, making research a truly campuswide enterprise.
At Uppsala University research is being conducted to understand our society, make the world better and make life simpler. Research that offers new perspectives on fundamental scientific questions as well as contributing to a sustainable environment, human health and the development of society.
Utrecht University is a research university comprised of seven faculties which collectively cover the full spectrum of research and education.
The Wadsworth Center laboratories stand at the forefront of biomedical and environmental sciences and their interplay. The Center serves a vital role in the Health Department's efforts to protect and promote the health of New York's citizens.
Wake Forest School of Medicine (WFSM) occupies a firm position among the best medical schools in the United States. The desire to teach excellence in clinical medicine, promote strong clinical and basic research, render exemplary patient care, and stress service to the community has continued as an integral part of Wake Forest Baptist Medical Center, a leading research and teaching hospital.
Headquartered in Madison, Wisconsin, WiCell is a supporting organization of the University of Wisconsin–Madison, a world leader in the area of human pluripotent stem cell research. WiCell is a nonprofit organization established in 1999 to advance the science of stem cells. The global leader in cell banking, cytogenetic testing and distribution of stem cell lines, WiCell builds on these core strengths by also providing clinical grade pluripotent stem cell lines, quality control testing and cell banking services.
Found 79 resource providers .