eagle-i eagle-i Network Shared Resource Repositoryeagle-i Network Shared Resource Repository
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

ATCC-DYP0250 Human Induced Pluripotent Stem Cells (ATCC® ACS-1004™)

eagle-i ID


Resource Type

  1. Induced pluripotent stem cell line


  1. Source Human Subject
    CCD-186Sk (ATCC CRL-1563)-HS
  2. Exchange facilitator
    <html><a href="http://www.atcc.org/Products/Cells_and_Microorganisms/Stem_Cells/Human_IPS_Pluripotent/ACS-1004.aspx"><b>Order this cell line from ATCC</b></a></html>
  3. Induction Reagents
    OCT4, SOX2, KLF4, MYC
  4. Resource Description
    ATCC-DYP0250 Human Induced Pluripotent Stem Cells (iPSCs) were derived from dermal fibroblasts obtained from ATCC CRL1563 CCD186Sk, a human cystic fibrosis cell line. The fibroblasts were reprogrammed by the transient expression of OCT4, SOX2, KLF4 and MYC gene sequences using nonintegrating episomal plasmids. This cell line provides a unique model system for better understanding the molecular pathology associated with cystic fibrosis.
  5. Related Disease
    cystic fibrosis
  6. Website(s)
  7. Genetic Alteration(s)
  8. Source Anatomical Structure
    Skin of prepuce of penis
  9. Source Organism Type
  10. Catalog Number
  11. Parental Line
    CCD-186Sk (ATCC® CRL-1563™)
  12. Subject Age at Sampling
  13. Induction Method
    Episomal plasmid induction
  14. Location
Provenance Metadata About This Resource Record

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016