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(WiCell) Sickle Cell Anemia Collection - Steinberg Lab

eagle-i ID


Resource Type

  1. Resource Collection


  1. Related grant number
  2. Resource Description
    This collection, from Dr. Martin Steinberg (Boston University), used erythroid cells from patient-specific iPSCs to study genetic factors modulating the severity of sickle cell anemia and its responsiveness to treatment. This study was largely centered on this feature of the disease where the quantitative trait loci evaluated affect fetal hemoglobin (HbF) expression. The iPS cell lines in this collection were banked and characterized in the laboratory of Dr. Gustavo Mostoslavsky, Boston University. This collection contains over 40 cell lines. Individuals giving rise to iPSC lines were of African American or Arab descent. Disease states for the subjects include sickle cell anemia as well as no reported diagnoses. Age of donors range from 3-45 years.
  3. Additional Name
    NHLBI Next Gen – Sickle Cell Anemia (Dr. Martin Steinberg, Boston University)
  4. Contact
    Steinberg, Martin, M.D.
  5. Topic
    sickle cell anemia
  6. Website(s)
  7. Funded by
    National Heart, Lung, and Blood Institute
  8. Developed by
    Steinberg Lab
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