eagle-i eagle-i Network Shared Resource Repositoryeagle-i Network Shared Resource Repository
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

(WiCell) Sickle Cell Anemia Collection - Steinberg Lab

eagle-i ID

http://shared.eagle-i.net/i/0000015a-1668-f06c-49f6-255680000000

Resource Type

  1. Resource Collection

Properties

  1. Related grant number
    5U01HL107443-05
  2. Resource Description
    This collection, from Dr. Martin Steinberg (Boston University), used erythroid cells from patient-specific iPSCs to study genetic factors modulating the severity of sickle cell anemia and its responsiveness to treatment. This study was largely centered on this feature of the disease where the quantitative trait loci evaluated affect fetal hemoglobin (HbF) expression. The iPS cell lines in this collection were banked and characterized in the laboratory of Dr. Gustavo Mostoslavsky, Boston University. This collection contains over 40 cell lines. Individuals giving rise to iPSC lines were of African American or Arab descent. Disease states for the subjects include sickle cell anemia as well as no reported diagnoses. Age of donors range from 3-45 years.
  3. Additional Name
    NHLBI Next Gen – Sickle Cell Anemia (Dr. Martin Steinberg, Boston University)
  4. Contact
    Steinberg, Martin, M.D.
  5. Topic
    sickle cell anemia
  6. Website(s)
    http://www.wicell.org/home/stem-cell-lines/catalog-of-stem-cell-lines/collections/nhlbi-next-gen-steinberg.cmsx
  7. Funded by
    National Heart, Lung, and Blood Institute
  8. Developed by
    Steinberg Lab
 
RDFRDF
 
Provenance Metadata About This Resource Record

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016